Graham Richard Williams

The paper maps the osteocyte transcriptome in mice, identifies 1239 genes, and links them to skeletal disease susceptibility in humans.

The paper identifies 14 genes involved in osteoarthritis using mutant mice and validates their role through functional studies and genome editing.

This study identifies molecular subgroups of osteoarthritis and develops a 7-gene classifier to stratify patients, while uncovering potential therapeutic compounds.

This paper identifies 518 genetic loci associated with bone mineral density and fracture risk, validates causal genes in mice, and provides insights for osteoporosis drug development.