Author

Shimpei Gotoh

Kyoto UniversityORCID 0000-0002-8563-8200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Mio IwasakiiD· 2 shared Naoyuki SoneiD· 2 shared Takuya YamamotoiD· 2 shared Abeer KeshtaiD· 1 shared Akira NiwaiD· 1 shared Akira YamagataiD· 1 shared Atsushi SaitoiD· 1 shared Hirofumi ChibaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Mio IwasakiORCID

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2 papers

Recent·Most cited

Human club cells derived from pluripotent stem cells reveal new insights into epithelial lineage plasticity through structural and functional validation

Naoyuki Sone, Naoki Fujiwara, Abeer Keshta, Satoshi Konishi, Manabu Toyoshima, Tomoyuki Takaku, Yasuhiko Takahashi, Mio Iwasaki, Takuya Yamamoto, Shimpei Gotoh

This study generates human club cells from pluripotent stem cells, revealing epithelial plasticity and new differentiation trajectories.

bioRxiv · May 22, 2026 · PreprintCell Biology

In vivo xenogenic reconstitution of human alveolar epithelial architecture and function

Akira Yamagata, Satoshi Konishi, Satoshi Ikeo, Hiroshi Moriyama, Senye Takahashi, Naoyuki Sone, Satoshi Hamada, Atsushi Saito, Takashi Kawaguchi, Shu Hisata, Akira Niwa, Toshiaki Kikuchi, Hirofumi Chiba, Megumu K. Saito, Koichi Hagiwara, , Shimpei Gotoh

This paper develops a chimeric mouse model to replicate human alveolar epithelial architecture and function using hiPSC-derived lung progenitors.

bioRxiv · Jan 12, 2026 · PreprintDevelopmental Biology