Mio Iwasaki

This study shows sonication causes selective fragmentation of intrinsically disordered proteins in proteomics, leading to structural bias and potential misinterpretation of protein size and stability.

This study generates human club cells from pluripotent stem cells, revealing epithelial plasticity and new differentiation trajectories.

This paper develops a chimeric mouse model to replicate human alveolar epithelial architecture and function using hiPSC-derived lung progenitors.

This study shows that eIF4G2 is essential for intestinal stem cell maintenance and differentiation by facilitating the translation of histone modifiers.

The paper identifies 20 post-transcriptionally regulated genes essential for pluripotent stem cell survival, showing their protein upregulation and nuclear-to-cytoplasmic mRNA localization.