Megumu K. Saito

This paper develops a chimeric mouse model to replicate human alveolar epithelial architecture and function using hiPSC-derived lung progenitors.

This study develops CAR-macrophages from pluripotent stem cell-derived myeloid cell lines for enhanced anti-tumor effects through repeated administration.

This study models the human segmentation clock using iPSC-derived presomitic mesoderm, identifying oscillatory genes and validating disease-related gene effects.

This study identifies that HUVECs amplify erythroid cells through secreted angiocrine factors by maintaining their undifferentiated state and activating ERK signaling.