Author

Erica L. Kleinbrink

Wayne State UniversityORCID 0000-0002-8565-207XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alisa Knodle ManningiD· 2 shared Aaron LeongiD· 1 shared Abbas DehghaniD· 1 shared Albert V. SmithiD· 1 shared Andrei I. Tarasov· 1 shared Andrianos M. Yiorkas· 1 shared Anne E Justice· 1 shared Anne Raimondo· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Alisa Knodle ManningORCID

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2 papers

Recent·Most cited

A long noncoding RNA, LOC157273, is the effector transcript at the chromosome 8p23.1-PPP1R3B metabolic traits and type 2 diabetes risk locus

Alisa Knodle Manning, Anton Scott Goustin, Erica L. Kleinbrink, Pattaraporn Thepsuwan, Juan Cai, Donghong Ju, Aaron Leong, Miriam S. Udler, James Bentley Brown, Mark O. Goodarzi, Jerome I. Rotter, ROBERT M. SLADEK, James B. Meigs, Leonard Lipovich

The paper identifies LOC157273 as a negative regulator of PPP1R3B and glycogen deposition in human hepatocytes, linking it to type 2 diabetes risk.

Frontiers in Genetics · Jul 10, 2020Peer-reviewedGenomics

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

Natasha Hui Jin Ng, Sara M. Willems, Juan Fernandez, Rebecca S. Fine, Eleanor Wheeler, Jennifer Wessel, Hidetoshi Kitajima, Gaëlle Marenne, Jana K. Rundle, Xueling Sim, Hanieh Yeghootkar, Nicola L. Beer, Anne Raimondo, Andrei I. Tarasov, Soren K. Thomsen, , Abbas Dehghan

The paper identifies genetic variants and transcripts associated with glycemic traits by analyzing exome-array data from 144,600 individuals, highlighting tissue-specific roles in glucose regulation.

bioRxiv · Oct 3, 2019 · PreprintGenetics