Donghong Ju

This study shows that N-terminal intrinsically disordered regions (IDRs) suppress cotranslational protein degradation in yeast and human cells by recruiting HSP70 chaperones.

This paper develops a mouse model with a FBN1 nonsense mutation to study aneurysm progression, finding that adventitial inflammation contributes to aortic aneurysm rupture.

The paper identifies LOC157273 as a negative regulator of PPP1R3B and glycogen deposition in human hepatocytes, linking it to type 2 diabetes risk.