Colorectal ALOX15 as a host factor determinant of EPA and DHA effects on colorectal carcinogenesis
Xiangsheng Zuo, Yoshiyuki Kiyasu, Yi Liu, Yasunori Deguchi, Fuyao Liu, Micheline J. Moussalli, Lin Tan, Bo Wei, Daoyan Wei, Peiying Yang, Imad Shureiqi
This study shows that ALOX15 expression modulates EPA and DHA effects on colorectal carcinogenesis by promoting resolvin generation, which suppresses pro-tumorigenic inflammation.
Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2025Peer-reviewedCancer Biology