Lin Tan

This study shows that reduced hepatic pyrimidine synthesis during fasting and obesity promotes insulin resistance and obesity by increasing hepatic glucose production and decreasing insulin clearance.

This study shows that ALOX15 expression modulates EPA and DHA effects on colorectal carcinogenesis by promoting resolvin generation, which suppresses pro-tumorigenic inflammation.

This paper investigates how gold nanocrystals regulate bioenergetic metabolism by catalyzing NADH oxidation, enhancing ATP production, and improving neuronal survival under stress.

This study shows that D2-HG induces cachexia in mice by disrupting NAD+ homeostasis and autophagy, revealing metabolic vulnerabilities in skeletal muscle.