Author

Christopher Tai-Yi Lee

National Institutes of HealthORCID 0000-0002-8621-256XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:long-read sequencing· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Abid RehmaniD· 1 shared Alan P. BoyleiD· 1 shared Cédric BelairiD· 1 shared Chee Khoon LeeiD· 1 shared Katarína GrešováiD· 1 shared Lin WangiD· 1 shared Manolis MaragkakisiD· 1 shared Mark CooksoniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Abid RehmanORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 5, 2025

Cell-specific RNA isoform remodeling in the aging mouse brain

Abid Rehman, Megan F. Duffy, Katarína Grešová…·Manolis Maragkakis

This study identifies cell-type-specific RNA isoform changes in aging mouse brain using single-cell and long-read sequencing, revealing altered coding potential and senescence markers in immune cells.

DOI 10.1101/2025.06.05.658133

mousescRNA-seq

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BioinformaticsNAR Genomics and BioinformaticsPeer-reviewedFeb 6, 2020

Poly-Enrich: Count-based Methods for Gene Set Enrichment Testing with Genomic Regions

Christopher Tai-Yi Lee, Raymond G. Cavalcante, Chee Khoon Lee…·Maureen A. Sartor

Poly-Enrich improves gene set enrichment testing for genomic regions by modeling peak counts with a negative binomial model, outperforming previous methods in certain scenarios.

22 citations

ChIP-seqstatistical model

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