Author

Diego López Mateos

University of California, DavisORCID 0000-0002-8627-7208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:Arabidopsis· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Vladimir M. Yarov-YarovoyiD· 2 shared Alice PierceiD· 1 shared Alissza AliiD· 1 shared Daniela QuiroziD· 1 shared J. Grey MonroeiD· 1 shared Justin B. SiegeliD· 1 shared Kehan ZhaoiD· 1 shared Kush NarangiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

Vladimir M. Yarov-YarovoyORCID

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3 papers

Recent·Most cited

Exploring voltage-gated sodium channel conformations and protein-protein interactions using AlphaFold2

Diego López Mateos, Kush Narang, Vladimir M. Yarov-Yarovoy

This study uses AlphaFold2 to model multiple conformations of voltage-gated sodium channels and their interactions with protein partners, revealing structural diversity and conformational changes.

The Journal of General Physiology · Dec 1, 2025Peer-reviewedBiophysics

Computational Drug Design of Novel Agonists of the μ-Opioid Receptor to Inhibit Pain Signaling

Nancy Daoud, Diego López Mateos, Mary Ann Riley, Justin B. Siegel

The paper computationally designs two novel μ-opioid receptor agonists with improved docking scores and ADMET properties compared to Hydrocodone.

bioRxiv · Aug 25, 2023 · PreprintMolecular Biology

The H3K4me1 histone mark recruits DNA repair to functionally constrained genomic regions in plants

Daniela Quiroz, Diego López Mateos, Kehan Zhao, Alice Pierce, Lissandro Ortega, Alissza Ali, Pablo Carbonell‐Bejerano, Vladimir M. Yarov-Yarovoy, J. Grey Monroe

The paper shows H3K4me1 recruits DNA repair proteins to reduce mutations in functionally constrained regions of plant genomes.

bioRxiv · May 28, 2022 · PreprintGenomics