Nuclear Calprotectin mediates Epithelial Wound Healing Defects in Crohns Disease related Fistula
Marte A. J. Becker, Pim J. Koelink, Sarah Ouahoud, Sander Meisner, Manon van Roest, Vanesa Muncan, Andreas P. Frei, Gerald H. Nabozny, Frank Li, Job Saris, Dalia A. Lartey, Willem Adrianus Bemelman, Geert D’Haens, Christianne Johanna Buskens, Manon E. Wildenberg
The paper identifies S100A8/9 as a transcriptional regulator involved in defective wound healing in Crohn's disease-related fistulas, highlighting distinct immune pathways in healing efficiency.
bioRxiv · Mar 6, 2025 · PreprintCell Biology