Single-cell characterization of tumor immune landscapes in colorectal cancer humanized mice
Sanne Bootsma, Job Saris, Andrew Y. F. Li Yim, Kristiaan Lenos, Felipe A. Vieira Braga, Joep Grootjans, Louis Vermeulen
This study uses single-cell RNA sequencing to analyze immune landscapes in humanized mice with colorectal cancer, showing complex human-like immune infiltrates and subtype-specific immune differences.
bioRxiv · Jun 4, 2026 · PreprintCancer Biology