Cell BiologybioRxivPreprint
CREG1 promotes autophagy and protects the heart against nutritional stress-induced injury and age-associated hypertrophy, fibrosis and diastolic dysfunction
Yanmei Qi, Russell Pepe, Glenn Tejeda…·Leonard Y. Lee
This study shows that CREG1 promotes autophagy and protects the heart from nutritional stress and age-related damage by maintaining autophagic flux and preventing mitochondrial dysfunction.
DOI 10.1101/2025.11.11.687936