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The paper evaluates RNA-Seq workflows for plasma cell-free transcriptome profiling, finding that technical factors dominate variability over biological differences.

The paper demonstrates that PCR errors significantly affect UMI-based absolute counting in sequencing data and proposes a solution using homotrimeric nucleotide blocks to correct these errors.

This study quantifies the contribution of transcriptional silencing and RNA degradation to heterochromatic silencing in fission yeast, revealing transcriptional efficiency as a new mechanism.

This paper introduces Trajan, a tool for comparing complex single-cell trajectories with branching points, demonstrating its ability to align biological processes and identify reprogramming barriers.