Author

William A. Ng

University of WaterlooORCID 0000-0002-8708-1880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Bruce H. ReediD· 2 shared Andrew MaiD· 1 shared Molly CheniD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersGenetics

Bruce H. ReedORCID

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2 papers

Recent·Most cited

GeneticsG3 Genes Genomes GeneticsPeer-reviewedApr 21, 2020

A method for rapid selection of randomly induced mutations in a gene of interest using CRISPR/Cas9 mediated activation of gene expression.

William A. Ng, Andrew Ma, Molly Chen, Bruce H. Reed

This paper describes a CRISPR/Cas9 method to select recessive lethal mutations in a gene of interest by overexpressing wild-type and loss-of-function alleles in Drosophila.

1 citation

DrosophilaCRISPR screen

GeneticsbioRxivPreprintOct 22, 2019

A method to estimate the frequency of chromosomal rearrangements induced by CRISPR/Cas9 multiplexing in Drosophila.

William A. Ng, Bruce H. Reed

The paper demonstrates that CRISPR/Cas9 multiplexing can induce chromosomal rearrangements in Drosophila, but the recovery frequency is low.

1 citation

Drosophilaexperimental assay