Bruce H. Reed

This study identifies ZDHHC17 as a key enzyme linking S-acylation to neurodegenerative diseases by modulating protein localization and toxicity.

The paper shows that 20E signaling modulates gene expression during Drosophila dorsal closure through a novel mechanism involving EcR and Jun interaction, distinct from canonical EcR-EcRE binding.

This paper describes a CRISPR/Cas9 method to select recessive lethal mutations in a gene of interest by overexpressing wild-type and loss-of-function alleles in Drosophila.

This study shows that the Drosophila gene hindsight positively regulates EGFR signaling through multiple developmental processes and genetic interactions.

The paper demonstrates that CRISPR/Cas9 multiplexing can induce chromosomal rearrangements in Drosophila, but the recovery frequency is low.