Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single cell resolution
Marina Ainciburu, Teresa Ezponda, Nerea Berastegui, Ana Alfonso Piérola, Amaia Vilas‐Zornoza, Patxi San Martín‐Úriz, Diego Alignani, José María Lamo-Espinosa, Mikel San-Julián, Tamara Jiménez, Félix López, Sandra Muntión, Fermin M. Sanchez-Guijo, Antonieta Molero, María Julia Montoro, , Felipe Prósper
This study uses single-cell RNA sequencing to analyze changes in hematopoietic stem and progenitor cells during aging and myeloid malignancies, identifying altered gene expression and regulatory networks.
eLife · Jan 11, 2023Peer-reviewedGenomics