Author

Ana Alfonso Piérola

Clinica Universidad de NavarraORCID 0000-0002-2478-5354Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Felipe PrósperiD· 3 shared Mikel HernáeziD· 3 shared Patxi San Martín‐ÚriziD· 3 shared Diego AlignaniiD· 2 shared Elena IglesiasiD· 2 shared Fermin M. Sanchez-GuijoiD· 2 shared Guillermo SerranoiD· 2 shared Juan José LasarteiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Felipe PrósperORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 5, 2026

Rational engineering of sdAb-based CAR T cells targeting BCMA enhances antitumor efficacy and persistence in Multiple Myeloma

Vianca Ibarra-Garcia, María Eréndira Calleja-Cervantes, Federica Rochira…·Felipe Prósper

This study engineers sdAb-based CAR T cells targeting BCMA, showing improved antitumor efficacy and persistence in multiple myeloma compared to existing therapies.

DOI 10.64898/2026.06.02.729637

humanscRNA-seq

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GenomicsBlood NeoplasiaPeer-reviewedFeb 5, 2026

Single-Cell Multiomics Reveals Regulatory Mechanisms of CAR T Cell Persistence and Dysfunction in Multiple Myeloma

Lorea Jordana-Urriza, Guillermo Serrano, Sergio Camara-Peña…·Felipe Prósper

This study uses single-cell multiomics to analyze CAR T cell dynamics in multiple myeloma, identifying regulatory mechanisms affecting persistence and dysfunction.

6 citationstop 1%

humanscRNA-seq

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GenomicseLifePeer-reviewedJan 11, 2023

Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single cell resolution

Marina Ainciburu, Teresa Ezponda, Nerea Berastegui…·Felipe Prósper

This study uses single-cell RNA sequencing to analyze changes in hematopoietic stem and progenitor cells during aging and myeloid malignancies, identifying altered gene expression and regulatory networks.

68 citationstop 2%

humanscRNA-seq

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