Immunologynpj VaccinesPeer-reviewed
Matrix-M(R) adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization
Behdad Zarnegar, Berit Carow, Jens Eriksson…·Carolina Lunderius-Andersson
This study shows Matrix-M adjuvant induces lysosomal membrane permeabilization, enabling antigen cross-presentation and IL-1β/IL-18 secretion, which contributes to its adjuvant effect.
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