GenomicsCellular and Molecular Gastroenterology and HepatologyPeer-reviewed
Single-Cell Analysis Reveals Regional Reprogramming during Adaptation to Massive Small Bowel Resection in Mice
Kristen M. Seiler, Sarah E. Waye, Wenjun Kong…·Samantha A. Morris
The paper uses single-cell RNA sequencing to show that mice adapt to small bowel resection by reprogramming distal intestinal enterocytes to a proximal identity, driven by retinoid metabolism and Creb3l3.