Cancer BiologybioRxivPreprint
C9orf50 is a Targetable Spliceosome Regulator for Cancer Immunotherapy
Tong Shao, Chuanyang Liu, Jingyu Kuang…·Lvyun Zhu
This study identifies C9orf50 as a spliceosome regulator that, when targeted, converts immunologically cold tumors to hot ones by enhancing immunogenicity and T cell recruitment.
DOI 10.1101/2025.03.13.642772