Real-time visualization of mRNA synthesis during memory formation in live animals
Byung Hun Lee, Jae Youn Shim, Hyungseok C. Moon, Dong Wook Kim, Jiwon Kim, Jang Soo Yook, Jinhyun Kim, Hye Yoon Park
The paper uses a genetically-encoded RNA indicator to visualize Arc mRNA dynamics in live animals during memory formation and retrieval, revealing rapid turnover in hippocampal neurons and stable expression in retrosplenial cortex neurons.
Proceedings of the National Academy of Sciences · Jul 1, 2022Peer-reviewedNeuroscience