Eiji Yamamoto

The paper develops coarse-grained models for simulating double-stranded RNA and DNA in the CALVADOS framework to study their behavior in protein-nucleic acid condensates.

The paper uses simulations to study how proteins partition into MED1 and FUS condensates, identifying sequence features that predict partitioning and developing a sequence-based predictor.

This paper introduces a coarse-grained RNA model to simulate protein-RNA condensates and shows it captures key interaction aspects.

The paper develops a method to engineer lipid-binding probes by screening protein-lipid interactions and identifies structural features that enhance binding to phosphatidylinositol phosphates.