Radiation-Induced Collagen I&III Accumulation Drives Immunosuppressive Evolution in Recurrent Glioblastoma
Opeyemi Iwaloye, Lewis Barr, Jun Takei, Shunsuke Tsuzuki, Harish Kumar, Satoru Osuka
This study identifies radiation-induced collagen I&III accumulation as a driver of immunosuppressive evolution in recurrent glioblastoma and shows that targeting this pathway improves immunotherapy outcomes.
bioRxiv · Oct 20, 2026 · PreprintCancer Biology