Kimberly Laskie Ostrow

This paper investigates how schwannoma-induced pain is mediated by mechanosensitive ion channels and shows that GsMTx-4 can reduce mechanosensitivity in a schwannomatosis model.

This study shows that conditioned medium from painful schwannomatosis tumors induces pain behaviors in mice, with effects varying based on tumor mutations.

The paper shows that conditioned medium from painful schwannomatosis tumors sensitizes sensory neurons more than nonpainful tumors, indicating secreted factors contribute to pain variability.