Author

Johan Zvrskovec

King's College LondonORCID 0000-0002-8862-0874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Christopher HübeliD· 2 shared Gerome D. BreeniD· 2 shared Jonathan R. I. ColemaniD· 2 shared Abigail ter KuileiD· 1 shared Alexandra C. GillettiD· 1 shared Alexei Moulton· 1 shared Alicia J. PeeliD· 1 shared Alish PalmosiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Christopher HübelORCID

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2 papers

Recent·Most cited

Genome-wide genetic overlap between fear-based disorders and generalised anxiety disorder

Abigail ter Kuile, Brittany L. Mitchell, Sang Hyuck Lee, Geneviève Morneau‐Vaillancourt, Megan Skelton, Jonathan R. I. Coleman, Helena L. Davies, Jessica Mundy, Alicia J. Peel, Christopher Hübel, Molly Rose Davies, Anna Elisabeth Fürtjes, Zain Ahmad, Yuhao Lin, Brett N. Adey, , Thalia Catherine Eley

This study identifies genetic differences between fear-based anxiety disorders and generalised anxiety disorder using GWAS, finding partial genetic distinction and shared liability to internalising psychopathology.

Molecular Psychiatry · Jun 29, 2026Peer-reviewedGenetic & Genomic Medicine

LDSC++: Improving linkage disequilibrium score regression estimation of heritability and genetic correlation for multivariate GWAS analysis

Johan Zvrskovec, Alexandra C. Gillett, Michel Guillaume Nivard, Jonathan R. I. Coleman, Christopher Hübel, Raquel Iniesta, Gerome D. Breen

LDSC++ improves heritability and genetic correlation estimation in multivariate GWAS by enhancing LD score regression with segmented regression and better handling of shared genetic variants and imputation quality.

medRxiv · Apr 7, 2025 · PreprintGenetic & Genomic Medicine