NeuroscienceMolecular Therapy — Nucleic AcidsPeer-reviewed
Rheb-mTOR Activation Rescues Amyloid Beta-Induced Cognitive Impairment and Memory Function by Restoring miR-146 Activity in Glial Cells
Dipayan De, Ishita Mukherjee, Subhalakshmi Guha…·Suvendra N. Bhattacharyya
The paper identifies that Rheb-mTOR activation restores miR-146 activity in glial cells, reducing amyloid beta-induced cytokine production and rescuing cognitive impairment in a rat Alzheimer's model.
27 citations