Molecular BiologybioRxivPreprint
Alzheimer's disease-associated P460L mutation in ephrin receptor type A1 (EphA1) leads to dysregulated Rho-GTPase signaling
Y. Kim, Gorka Lasso, Hardik Patel…·Roger Lefort
The paper investigates the impact of the EphA1 P460L mutation on Rho-GTPase signaling in Alzheimer's disease, showing it leads to constitutive receptor activity and dysregulated signaling.
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