Author

Ingrid Hoffmann

German Cancer Research CenterORCID 0000-0002-8894-8597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ferris JungiD· 1 shared H. Kübra Gürkaşlar· 1 shared Johanna Melisa TocciiD· 1 shared Maria Lucia Pigazzini· 1 shared Mathias BoulangeriD· 1 shared Niccolò BanterleiD· 1 shared Vladimı́r BenešiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Ferris JungORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 23, 2026

Lack of centrosomes limits the epithelial-to-mesenchymal transition in human mammary cells

Maria Lucia Pigazzini, Johanna Melisa Tocci, Mathias Boulanger…·Niccolò Banterle

The paper shows that centrosome absence inhibits cytoskeletal remodeling during EMT in breast cells, despite some nuclear changes and EMT marker upregulation.

DOI 10.64898/2026.09.18.752689

humanbulk RNA-seq

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Cell BiologyMolecular Biology of the CellPeer-reviewedMay 15, 2025

Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly

H. Kübra Gürkaşlar, Ingrid Hoffmann

This study shows that CEP152 binds to PLK4, enhancing its kinase activity and promoting centriole assembly by stabilizing PLK4 dimer formation and autophosphorylation.

3 citations

humanexperimental assay

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