Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3
Sophie Bérenger, Justyna M. Adamska, Francesca Deflorian, Chris de Graaf, Christie B. Palmer, Martyna Szpakowska, Andy Chevigné, Iwan J. P. de Esch, Barbara A. Zarzycka, Henry F. Vischer, Maikel Wijtmans, Rob Leurs
This paper designs and characterizes the first photoswitchable small-molecule agonist for ACKR3, showing its selectivity and light-controlled activation properties.
ACS Omega · Feb 18, 2025Peer-reviewedPharmacology & Toxicology