Author

Deepa Singh

All India Institute of Medical SciencesORCID 0000-0002-8912-3263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Arkadyuti GhoraiiD· 1 shared Deepak SehgaliD· 1 shared Kamal BaswaliD· 1 shared Krishna Kishore InampudiiD· 1 shared Madhumohan Rao KatikaiD· 1 shared Manoj KumariD· 1 shared Marceline CôtéiD· 1 shared Mohan Babu AppaiahgariiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Arkadyuti GhoraiORCID

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1 paper

Recent·Most cited

Interaction of SCoV-2 NSP7 or NSP8 alone with NSP12 causes constriction of the RNA entry channel: Implications for novel RdRp inhibitor drug discovery

Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H Tiwari, Arkadyuti Ghorai, Manoj Kumar, Saroj Kumar, Polamarasetty Aparoy, Deepak Sehgal, Madhumohan Rao Katika, Suresh Gadde, Marceline Côté, Sarala Rani Kayampeta, , Krishna Kishore Inampudi

The paper studies how NSP7 and NSP8 interact with NSP12 to affect RNA replication in SCoV-2 and suggests potential drug targets by showing that their absence blocks polymerase activity.

bioRxiv · Jul 26, 2023 · PreprintMolecular Biology