Molecular BiologybioRxivPreprint
Interaction of SCoV-2 NSP7 or NSP8 alone with NSP12 causes constriction of the RNA entry channel: Implications for novel RdRp inhibitor drug discovery
Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy…·Krishna Kishore Inampudi
The paper studies how NSP7 and NSP8 interact with NSP12 to affect RNA replication in SCoV-2 and suggests potential drug targets by showing that their absence blocks polymerase activity.
DOI 10.1101/2023.07.26.550660