Disrupted bone microenvironment and immune recovery following total body irradiation in a murine model
Tibor Sághy, Priti Gupta, Karin Horkeby, Petra Henning, Claes Ohlsson, Carmen Corciulo, Marie K. Lagerquist, Andrei S. Chagin, Cecilia Engdahl
This study investigates the effects of total body irradiation on bone microenvironment and immune recovery in a murine model, finding persistent apoptotic cells and TGF-β1 signaling contribute to impaired bone remodeling.
Cell Death and Disease · Dec 13, 2025Peer-reviewedMolecular Biology