Author

Andrei S. Chagin

University of GothenburgORCID 0000-0002-2696-5850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Claes OhlssoniD· 3 shared Dana TrompetiD· 2 shared Lars S SavendahliD· 2 shared Nelson Tsz Long Chu· 2 shared Ostap A. DregvaliD· 2 shared Xin TianiD· 2 shared Baoyi Zhou· 1 shared Björn BareniusiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Claes OhlssonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologyScience Translational MedicinePeer-reviewedApr 15, 2026

A transcriptional atlas of the pubertal human growth plate reveals direct stimulation of cartilage stem cells by growth hormone.

Nelson Tsz Long Chu, Ostap A. Dregval, Farasat Zaman…·Andrei S. Chagin

This study reveals GH directly stimulates human growth plate stem cell proliferation via TGF{beta} and ERK pathways, offering insights into growth mechanisms and treatment optimization.

4 citationstop 1%

humanbulk RNA-seq

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Molecular BiologyCell Death and DiseasePeer-reviewedDec 13, 2025

Disrupted bone microenvironment and immune recovery following total body irradiation in a murine model

Tibor Sághy, Priti Gupta, Karin Horkeby…·Cecilia Engdahl

This study investigates the effects of total body irradiation on bone microenvironment and immune recovery in a murine model, finding persistent apoptotic cells and TGF-β1 signaling contribute to impaired bone remodeling.

4 citations

mousebulk RNA-seq

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Cell BiologybioRxivPreprintOct 7, 2025

Quantitative Multicolored Deep Imaging of Human Bones Reveals a Composite Osteo-Sinusoidal Niche for Mesenchymal Stromal Cells.

Nelson Tsz Long Chu, Ostap A. Dregval, Yu‐Wei Chang…·Andrei S. Chagin

The paper uses a tissue-clearing protocol to spatially map BM-MSCs in human bones, revealing distinct microenvironment features in young and aged bones.

2 citations

humanspatial transcriptomics

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