Author

Chaitanya S. Mokashi

University of PittsburghORCID 0000-0002-8939-6958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Robin LeeiD· 2 shared Steven W. SmealiD· 2 shared A Hyun KimiD· 1 shared David L. Schipper· 1 shared Gabriel J. KowalczykiD· 1 shared J. Agustin CruziD· 1 shared Peter M. Chiknas· 1 shared Qiuhong ZhangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Robin LeeORCID

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2 papers

Recent·Most cited

Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics

Steven W. Smeal, Chaitanya S. Mokashi, A Hyun Kim, Peter M. Chiknas, Robin Lee

The paper shows that prolonged IKK activation from time-varying cytokine stimuli leads to nuclear NF-κB retention via chromatin remodeling, with simulations accurately predicting single-cell responses.

Nature Communications · Aug 8, 2025Peer-reviewedSystems Biology

A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB

J. Agustin Cruz, Chaitanya S. Mokashi, Gabriel J. Kowalczyk, Yue Guo, Qiuhong Zhang, Sanjana Gupta, David L. Schipper, Steven W. Smeal, Robin Lee

Science Advances · Jul 23, 2021Peer-reviewedSystems Biology