Author

A Hyun Kim

University of PittsburghORCID 0000-0002-9558-9529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Robin LeeiD· 2 shared Benjamin Krummenacher· 1 shared Chaitanya S. MokashiiD· 1 shared David Ryan KoesiD· 1 shared Jason YeungiD· 1 shared Peter M. Chiknas· 1 shared Steven W. SmealiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersSystems Biology

Robin LeeORCID

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2 papers

Recent·Most cited

NEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinity

A Hyun Kim, Benjamin Krummenacher, Jason Yeung, David Ryan Koes, Robin Lee

The paper investigates how IL-1 receptor signaling dynamics are quantized and independent of ligand affinity using experimental and modeling approaches.

Cell Reports · Dec 1, 2025Peer-reviewedSystems Biology

Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics

Steven W. Smeal, Chaitanya S. Mokashi, A Hyun Kim, Peter M. Chiknas, Robin Lee

The paper shows that prolonged IKK activation from time-varying cytokine stimuli leads to nuclear NF-κB retention via chromatin remodeling, with simulations accurately predicting single-cell responses.

Nature Communications · Aug 8, 2025Peer-reviewedSystems Biology