Starvation improves epithelial fitness by selectively extruding DNA damaged cells
Lily Gates, Dustin Bagley, Konstantinos Kalyviotis, John Fadul, Tania Auchynnikava, Maria Voronkov, Jody Rosenblatt
The paper shows that starvation-induced cell extrusion selectively removes DNA-damaged cells, improving tissue fitness through a p53-dependent pathway.
bioRxiv · Sep 24, 2026 · PreprintCell Biology