Author

Gianella Facchin

Universidad de la República de UruguayORCID 0000-0002-8960-2694Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Katherine Seneth Muñoz GarzóniD· 2 shared V. Martínez· 2 shared Verónica Celeste De GiustiiD· 2 shared A. L. Di Virgilio· 1 shared Ana Laura Di VirgilioiD· 1 shared Carlos Yañez Fernandez· 1 shared D. Pérez Visñuk· 1 shared Marcela Solange VillaverdeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

Katherine Seneth Muñoz GarzónORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 9, 2026

Methyl-substituted 1,10-phenanthroline derivatives in copper(II) complexes enhance antitumor activity and inhibit NHE1 in MDA-MB-231 breast cancer cells

Katherine Seneth Muñoz Garzón, Verónica Celeste De Giusti, Carlos Yañez Fernandez…·Ana Laura Di Virgilio

This study evaluates three copper(II) complexes with methyl-substituted phenanthroline ligands, showing enhanced antitumor activity against breast cancer cells through ROS-mediated apoptosis and NHE1 inhibition.

DOI 10.64898/2026.09.04.749506

humanproteomics

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Cancer BiologyJBIC Journal of Biological Inorganic ChemistryPeer-reviewedMar 21, 2026

Role of the NHE1 exchanger in the antitumor effects of copper(II) complexes and phenanthroline derivatives

Katherine Seneth Muñoz Garzón, V. Martínez, Verónica Celeste De Giusti…·A. L. Di Virgilio

This study evaluates copper(II) complexes and phenanthroline derivatives against breast cancer cells, showing antitumor effects and a role for NHE1 in cell migration.

1 citation

humanexperimental assay

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