Author

Xiaofeng Wu

The University of Texas Southwestern Medical CenterORCID 0000-0002-8961-2163Unclaimed ORCID profile · follow to get notified of new preprints

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Xiaofeng Wu1 paper · Huazhong Agricultural University

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein structure prediction· 1

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David H. MathewsiD· 1 shared James KimiD· 1 shared Jean Rene V. ClemenceauiD· 1 shared Jeremiah Herbert· 1 shared John Tyler Piazza· 1 shared Lawrence LumiD· 1 shared Quinn Barrett· 1 shared Rubina TuladhariD· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

David H. MathewsORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedSep 6, 2019

CRISPR/Cas9-based mutagenesis frequently provokes on-target mRNA misregulation

Rubina Tuladhar, Yunku Yeu, John Tyler Piazza…·Lawrence Lum

This study shows that CRISPR/Cas9-induced INDELs can lead to mRNA misregulation by creating foreign mRNAs or proteins in about half of edited cell lines.

219 citationstop 1%

humanCRISPR screen