Michael Milton

cellNexus: Quality control, annotation, aggregation and analytical layers for the Human Cell Atlas data

cellNexus enhances Human Cell Atlas data by adding quality control, metadata, normalization, and analysis layers to enable multi-study analyses and large-scale biological discovery.

Fast, accurate and scalable normalization for RNA sequencing data with the RUVprps software package

The paper introduces RUVprps, a software package for normalizing RNA-seq data by removing unwanted variation, offering improved performance and features for analysis.

Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson's disease cohorts

The paper screens whole genome sequencing data from PD and LBD cohorts to identify ATXN2 repeat expansions, finding them in cases but not controls.

Unveiling Peripheral Immune Dysfunction in Parkinson's Disease through Analysis of Blood-based Mitochondrial DNA Copy Number

This study investigates the association between blood mitochondrial DNA copy number and Parkinson's disease, finding that peripheral immune dysfunction, not mitochondrial dysfunction, underlies the observed associations.