Jiru Han

Genetic Risk of Reticular Pseudodrusen in Age-Related Macular Degeneration: HTRA1/lncRNA BX842242.1 dominates, with no evidence for Complement Cascade involvement

Single-cell transcriptomic dynamics exposes hidden survival trajectory under antibiotic treatment

This study uses single-cell RNA-seq to reveal concentration-dependent survival trajectories of Acinetobacter baumannii under antibiotic treatment, uncovering hidden heterogeneity and resistance mechanisms.

The genetic architecture of MRI derived human cervical spinal cord morphology reveals sensory-motor axis and biomarkers of neurological and systemic diseases

This study identifies genetic variants associated with cervical spinal cord morphology and links them to neurological and systemic diseases.

Identification of novel vertebral development factors through UK Biobank driven genetic and body imaging analysis reveals markers for back pain

The paper identifies three genes associated with vertebral variations and chronic pain using UK Biobank data and deep learning.

Unveiling Peripheral Immune Dysfunction in Parkinson's Disease through Analysis of Blood-based Mitochondrial DNA Copy Number

This study investigates the association between blood mitochondrial DNA copy number and Parkinson's disease, finding that peripheral immune dysfunction, not mitochondrial dysfunction, underlies the observed associations.

Population-level genome-wide STR typing in Plasmodium species reveals higher resolution population structure and genetic diversity relative to SNP typing

This study genotypes STRs in Plasmodium species using HipSTR and compares genetic diversity and population structure to SNP data, revealing higher resolution and unique signals.