Mapping 3D tissue orientation with tensor-augmented light-sheet microscopy
Mario Corral-Bolaños, Piyush Swami, Hanna Vila-Merkle, João Lima, Silja P Vange, Christophe Destrieux, Cyril Poupon, Jessica Pingel, Sanne Simone Kaalund, Lídia Bardia, Hans Martin Kjer, Marco Pizzolato, Jeppe Revall Frisvad, Julien Colombelli, Tim B. Dyrby
The paper introduces tLSSM, a label-free method for 3D fiber orientation mapping at micrometer resolution, demonstrating superior spatial resolution compared to diffusion MRI.
bioRxiv · May 8, 2026 · PreprintNeuroscience