Tim B. Dyrby

PhyMorphS generates realistic white matter microstructures using physics-guided mesh growth, reproducing key morphological features and enabling dMRI signal studies.

This paper introduces SMI, a quantitative MRI metric to assess myelin compact organisation, showing it detects structural abnormalities not captured by myelin content metrics.

The paper introduces tLSSM, a label-free method for 3D fiber orientation mapping at micrometer resolution, demonstrating superior spatial resolution compared to diffusion MRI.

This paper introduces EnCAR, a method for estimating asymmetric fiber orientation distribution functions in diffusion MRI, showing improved performance in complex regions.

The paper develops a deep learning framework for 3D segmentation of brain white matter microstructures from X-ray nano holography data, achieving high accuracy in complex anatomical regions.

The paper examines fibre organisation in white matter across species and anatomical scales using diffusion MRI and x-ray synchrotron imaging, finding common structural principles despite species-specific variations.

The paper compares structure-function relationships in axons using multiple modalities, finding that different methods capture different aspects of axon diameter and conduction velocity distributions.

The paper introduces the White Matter Generator tool to study how axon morphology and glial cell dynamics influence diffusion-weighted MRI signals in controlled white matter environments.

The paper shows that internal magnetic gradients affect diffusion MRI signals in myelinated axons, revealing morphology-dependent anisotropy previously unseen in 2D models.

The paper uses optogenetic stimulation to study transcallosal M1-M1 interactions in rats, finding a consistent negative peak response with variable amplitude and stable latency.

This study examines the effect of combined dexmedetomidine and isoflurane anaesthesia on visual evoked responses in rats, finding reduced but not fully suppressed responses in the visual cortex.

The paper evaluates powder averaging's effectiveness in diffusion MRI for axon diameter estimation in complex brain architectures, finding it accurate across parameters but sensitive to microdispersion at low b-values.

The paper shows that axon morphology is influenced by the local environment and affects diffusion MRI estimates of axon diameter and structure-function relationships.

The paper evaluates tractography reproducibility using empirical data from a single healthy volunteer scanned on two scanners, finding high consistency among top algorithms but variability due to tract volume containment.

The paper investigates the role of the dorsal hippocampal commissure in episodic memory using MRI tractography and finds a correlation between its microstructure and memory performance.

This study evaluates modern diffusion tractography methods using a standardized challenge, finding no significant improvement in anatomical accuracy despite methodological advances.

The paper evaluates tractography methods by analyzing a simulated dataset, finding that most algorithms generate many false-positive connections.