Author

João Lima

Amager HospitalORCID 0000-0002-6071-7148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Hanna Vila-Merkle· 2 shared Marco PizzolatoiD· 2 shared Mario Corral-BolañosiD· 2 shared Tim B. DyrbyiD· 2 shared Amy M. TayloriD· 1 shared Christophe DestrieuxiD· 1 shared Cyril PouponiD· 1 shared David M. BannermaniD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Hanna Vila-Merkle

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3 papers

Recent·Most cited

Quantitative MRI-based assessment of the ultrastructural compactness of myelin lamellae

Marcos E. Bolaños, Hanna Vila-Merkle, João Lima, Emma L. Thomson, Robin Krüger, Niccolò Peruzzi, Martin Bech, Marco Pizzolato, Tim B. Dyrby

This paper introduces SMI, a quantitative MRI metric to assess myelin compact organisation, showing it detects structural abnormalities not captured by myelin content metrics.

bioRxiv · Oct 6, 2026 · PreprintNeuroscience

Mapping 3D tissue orientation with tensor-augmented light-sheet microscopy

Mario Corral-Bolaños, Piyush Swami, Hanna Vila-Merkle, João Lima, Silja P Vange, Christophe Destrieux, Cyril Poupon, Jessica Pingel, Sanne Simone Kaalund, Lídia Bardia, Hans Martin Kjer, Marco Pizzolato, Jeppe Revall Frisvad, Julien Colombelli, Tim B. Dyrby

The paper introduces tLSSM, a label-free method for 3D fiber orientation mapping at micrometer resolution, demonstrating superior spatial resolution compared to diffusion MRI.

bioRxiv · May 8, 2026 · PreprintNeuroscience

Discriminative aversive learning and amygdala responsivity is enhanced in mice with reduced serotonin transporter activity

João Lima, Trevor Sharp, Amy M. Taylor, David M. Bannerman, Stephen B. McHugh

This study shows that reducing serotonin transporter activity in mice enhances aversive learning and amygdala responsivity, supporting a network plasticity theory of serotonin function.

bioRxiv · Jun 23, 2017 · PreprintNeuroscience