Author

Charlotte Thibeault

Charité – Universitätsmedizin BerlinORCID 0000-0002-8979-9386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Alice BrauniD· 2 shared Carsten SkurkiD· 2 shared A. Pesenti· 1 shared A. Pineda Juan· 1 shared Aaron Blandino OrtíziD· 1 shared Adolfo de SalazariD· 1 shared Adolfo Garrido Chercoles· 1 shared Adriana PalomiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alice BraunORCID

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3 papers

Recent·Most cited

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19

Morgan Essex, Belén Millet Pascual-Leone, Ulrike Löber, Mathias Kuhring, Bowen Zhang, Ulrike Brüning, Raphaela Fritsche‐Guenther, Marta Krzanowski, Facundo Fiocca Vernengo, Sophia Brumhard, Ivo Röwekamp, Agata Anna Bielecka, Till Robin Lesker, Emanuel Wyler, Markus Landthaler, , Bastian Opitz

This study links gut microbiota dysbiosis and altered tryptophan metabolism to increased inflammation in severe COVID-19 patients.

bioRxiv · Dec 2, 2022 · PreprintSystems Biology

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

Frauke C. Degenhardt, David Ellinghaus, Simonas Juzėnas, Jon Lerga-Jaso, Mareike Wendorff, Douglas Maya‐Miles, Florian Uellendahl-Werth, Hesham ElAbd, Malte Christoph Rühlemann, Jatin Arora, Onur Özer, Ole Bernt Lenning, Ronny Myhre, May Sissel Vadla, Eike Matthias Wacker, , Elio Scarpini

This study identifies a new susceptibility locus for severe COVID-19 through a detailed GWAS analysis in European populations, focusing on genetic variants associated with disease severity.

Human Molecular Genetics · Jul 15, 2022Peer-reviewedGenetic & Genomic Medicine

HLA-C* 04:01 is a Genetic Risk Allele for Severe Course of COVID-19

Weiner January, Phillip Suwalski, Manuel Holtgrewe, Charlotte Thibeault, Melina Müller, Dimitri Patriki, Claudia Quedenau, Ulrike Krüger, Tania Elisa, Lena Johanna Lippert, Stubbemann Paula, Real Luis Miguel, Sanchez Juan Macias, A. Pineda Juan, Marta Fernández‐Fuertes, , Bettina Heidecker

The paper identifies HLA-C* 04:01 as a genetic risk allele associated with increased intubation risk in severe COVID-19 cases, validated across multiple cohorts.

medRxiv · Dec 21, 2020 · PreprintGenetic & Genomic Medicine