NeurosciencebioRxivPreprint
Investigating the role of APOE: limitations of human pluripotent stem cell-derived cerebral organoids
Damián G. Hernández, Louise A. Rooney, Maciej Daniszewski…·Alice Pébay
This study evaluates the ability of cerebral organoids derived from APOE-edited human pluripotent stem cells to model Alzheimer's disease features, finding limited APOE effect and high variability in organoid development.
DOI 10.1101/2020.11.30.405654