Molecular BiologybioRxivPreprint
Structural and dynamical basis for the interaction of HSP70-EEVD with JDP Sis1
Carolina O. Matos, Gláucia M.S. Pinheiro, Ícaro Putinhon Caruso…·Carlos H.I. Ramos
This study uses NMR to show that the EEVD motif of HSP70 transiently binds multiple sites on Sis1, facilitating HSP70 interaction and client protein release.
DOI 10.1101/2022.11.26.517237