The hearing-essential intracellular domain of PCDH15 reveals a new layer of auditory mechanotransduction
J. Van De Velde, Ruxandra Bighiu, Nabanita Mandal, Karine Lapouge, Marie Skepö, Yann G.‐J. Sterckx, Christine Petit, Vincent Van Rompaey, Pieter Van Wielendaele
This study identifies the CD2 intracellular domain of PCDH15 as an intrinsically disordered polymer with biophysical properties relevant to auditory mechanotransduction.
bioRxiv · Sep 23, 2026 · PreprintBiophysics