BiophysicsbioRxivPreprint
Lipid nanoparticle induced model endosomal membrane disruption
Shreya Pramanik, Aishwarya Vasudevan, Zhenghua Liang…·Gaurav Sahay
This study uses GUVs to visualize how two LNPs, LP01 and BiP-20, disrupt endosomal membranes at different pH levels, showing that bulk pKa does not predict functional membrane interaction.
DOI 10.64898/2026.09.11.751062