Coin-tossing by Kinesin-1 Head and Tail Binding Collectively Drives Microtubule Patterns
Jashaswi Basu, Kajal Singh, Anita Jannasch, Chaitanya A. Athale
The paper shows that kinesin-1's head and tail domains collectively drive microtubule motion patterns through a coin-toss mechanism, with the tail acting as an active mechanical component.
bioRxiv · Aug 18, 2025 · PreprintBiophysics